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More powerful CYP3A4 inhibitors like ketoconazole or itraconazole could possibly be expected to possess increased consequences than noticed with saquinavir. A starting up dose of twenty five mg of VIAGRA ought to be regarded in clients having erythromycin or strong CYP3A4 inhibitors (including saquinavir, ketoconazole, itraconazole) [see DOSAGE AND

Right after either oral or intravenous administration, sildenafil is excreted as metabolites predominantly in the feces (around eighty% of administered oral dose) and also to a lesser extent while in the urine (approximately 13% in the administered oral dose).Sildenafil could cause a significant drop within your blood pressure when applied with nit